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Can You Apply Moisturiser After Azelaic Acid? Expert Tips Inside
Skin Care

Can You Apply Moisturiser After Azelaic Acid? Expert Tips Inside

27 June 2025

Can You Mix Azelaic Acid with Moisturiser? A Complete Guide

If you follow skincare trends, you’ve probably heard a lot about azelaic acid lately. It’s gaining fame as a powerful, yet gentle ingredient.

But if you’re new to it, don’t worry! Let’s break down what azelaic acid is and how you can best use it with your moisturiser.

What is Azelaic Acid?

Azelaic acid is a natural compound found in grains like barley and rye. It’s celebrated for its ability to tackle acne, rosacea, and uneven skin tone.

This ingredient works thanks to its antimicrobial and anti-inflammatory properties, calming irritated skin while fighting bacteria.

You can find azelaic acid in many over-the-counter skincare products, usually in concentrations of 15% or less.

For stronger effects, professional treatments like peels or facials may contain higher percentages. If you’re considering this, consulting a dermatologist is key to avoid irritation.

Azelaic acid offers benefits such as reducing redness, clearing blemishes, and improving skin texture, making it a versatile choice for many skin types.

Can You Mix Azelaic Acid with Moisturiser?

The short answer is yes, but it depends on your skincare routine and the products you use. Azelaic acid comes in various forms—serums, creams, toners, or cleansers—each affecting how you layer it with a moisturiser.

Moisturiser plays a crucial role in protecting and hydrating the skin. When combined correctly with azelaic acid, you can boost your skin’s health and reduce dryness or irritation.

How to Use Azelaic Acid with Moisturiser: Step-by-Step Routine

Here’s a simple, effective routine you can try to combine azelaic acid with moisturiser:

Start by cleansing your face thoroughly to remove dirt and impurities.

Use an exfoliating toner to gently sweep away dead skin cells and prep your skin.

Apply a serum containing hyaluronic acid. This ingredient locks in moisture and primes your skin for the next steps.

Next, apply a serum or cream with azelaic acid. This helps the acid absorb well and work on skin concerns like acne or redness.

Follow with a nourishing moisturiser to seal everything in and create a protective barrier on your skin.

Finish with a broad-spectrum sunscreen SPF 30 or higher if you are doing this routine in the morning. Protecting your skin from UV rays is vital.

This sequence allows each product to perform optimally without interfering with one another.

Why Moisturiser Matters in Your Routine

Many people underestimate moisturiser’s importance. Unlike serums, moisturisers mainly work on the skin’s surface. They don’t deeply penetrate but create a barrier that keeps moisture locked in.

This barrier also shields your skin from environmental aggressors like pollution and UV rays, which can cause premature aging and damage.

If your goal is to target specific skin concerns like hyperpigmentation or fine lines, serums are your best bet. Save moisturiser to support skin hydration and defense.

Should Azelaic Acid Go Before or After Moisturiser?

Generally, it’s best to apply azelaic acid before moisturiser. Doing so ensures the acid can penetrate your skin effectively.

First, apply any hydrating serums such as those with hyaluronic acid. These serums help counteract any drying effects azelaic acid might cause.

Then, apply azelaic acid so it can work on the skin directly. Finish with your moisturiser to protect the skin surface and lock in hydration.

However, if your azelaic acid product is a cream, it might already be moisturising enough to use alone. Always check the product instructions and how your skin reacts.

Can You Use Niacinamide and Azelaic Acid Together?

Yes! Niacinamide and azelaic acid make a fantastic team. Niacinamide is known for its pore-refining, anti-inflammatory, and skin barrier-strengthening properties.

Together, these two ingredients target acne, redness, and pigmentation. Niacinamide helps reduce dark spots and scarring caused by acne, while azelaic acid fights bacteria and calms inflammation.

Using them together can create a powerful routine that improves skin clarity and texture without irritation.

What About Salicylic Acid and Azelaic Acid?

Salicylic acid is a popular BHA exfoliant known for clearing clogged pores. Many people wonder if they can use salicylic acid alongside azelaic acid.

You can, but it’s best to alternate their use. For example, use azelaic acid on some days and salicylic acid on others, especially in your evening routine.

Using both acids on the same day may irritate sensitive skin. Alternating helps manage breakouts while protecting your skin’s natural barrier.

What Goes First: Niacinamide or Azelaic Acid?

Apply niacinamide before azelaic acid. Niacinamide is often in serum form with a lightweight texture, so it should go on first.

Niacinamide hydrates and calms the skin, making it more receptive to azelaic acid. This order helps prevent irritation like dryness, redness, or itching.

A general skincare rule is to apply products from thinnest to thickest consistency. This way, each product absorbs properly, and your skin gains maximum benefit.

Can You Apply Azelaic Acid on Wet Skin?

Unlike humectants like hyaluronic acid, azelaic acid doesn’t perform well on wet skin.

Apply azelaic acid only when your skin is semi-dry after cleansing and applying hydrating serums.

Applying it on damp skin may dilute the acid or cause it to spread unevenly, reducing its effectiveness.

Tips to Maximise the Benefits of Azelaic Acid and Moisturiser

Patch test any new product before full application to avoid irritation.

Start with lower concentrations of azelaic acid and gradually increase as your skin builds tolerance.

Use moisturisers with soothing ingredients like ceramides or glycerin to support your skin barrier.

Always apply sunscreen during the day to protect skin treated with acids from sun damage.

Listen to your skin. If you notice redness or excessive dryness, adjust your routine or consult a dermatologist.

Final Thoughts

Azelaic acid is a skincare gem that helps fight acne, redness, and pigmentation. When paired correctly with a moisturiser, it delivers great results without over-drying or irritating your skin.

Use it after hydrating serums and before your moisturiser for optimal absorption and protection.

Pairing azelaic acid with niacinamide or alternating it with salicylic acid can also boost your routine’s effectiveness.

Remember, every skin type is unique. Adjust your routine as needed and seek professional advice if unsure.

If you want to know more or have specific questions, our skin experts are always ready to help—just reach out on Instagram!

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